STRATEGIES AND TACTICS FOR FREE-RADICAL CARBOCYCLIZATION - SYNTHESIS OF POLYFUNCTIONALIZED CYCLOPENTANOID MOLECULES FROM CARBOHYDRATES

Authors
MARCOCONTELLES J RUIZ P MARTINEZ L MARTINEZGRAU A
Citation
J. Marcocontelles et al., STRATEGIES AND TACTICS FOR FREE-RADICAL CARBOCYCLIZATION - SYNTHESIS OF POLYFUNCTIONALIZED CYCLOPENTANOID MOLECULES FROM CARBOHYDRATES, Tetrahedron, 49(30), 1993, pp. 6669-6694
Citations number
57
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
49
Issue
30
Year of publication
1993
Pages
6669 - 6694
Database
ISI
SICI code
0040-4020(1993)49:30<6669:SATFFC>2.0.ZU;2-X
Abstract
The tributyltin hydride + azobisisobutyronitrile (AIBN) mediated free radical carbocyclization of precursors 1-9, 48 and 49 is described. Th e resulting carbocycles have been obtained in moderate yield and good diastereoselectivity. These polyfunctionalized, enantiomerically pure cyclopentane derivatives are useful intermediates for further manipula tion.