TITERS OF ANTIBODY TO MYCOPLASMA IN SERA OF PATIENTS INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS

Citation
Jg. Tully et al., TITERS OF ANTIBODY TO MYCOPLASMA IN SERA OF PATIENTS INFECTED WITH HUMAN-IMMUNODEFICIENCY-VIRUS, Clinical infectious diseases, 17, 1993, pp. 190000254-190000258
Citations number
24
Categorie Soggetti
Microbiology,Immunology
ISSN journal
10584838
Volume
17
Year of publication
1993
Supplement
1
Pages
190000254 - 190000258
Database
ISI
SICI code
1058-4838(1993)17:<190000254:TOATMI>2.0.ZU;2-4
Abstract
One hundred sixty-seven sera collected from human immunodeficiency vir us (HIV)-negative blood donors (n = 41), asymptomatic HIV-positive pat ients (n = 75), and patients with AIDS (n = 51) were compared in a met abolism inhibition serological test employing antigens to four distinc t Mycoplasma species. The proportion of sera with antibody titers of g reater-than-or-equal-to 1:32 to Mycoplasma genitalium was significantl y higher for patients with AIDS than for HIV-negative blood donors. Se rological relationships between Mycoplasma pneumoniae and M. genitaliu m as well as the possibility of increased susceptibility of AIDS patie nts to infection with these two mycoplasmas might account for this fin ding. Few sera showed antibody responses to Mycoplasma pirum or Mycopl asma fermentans.