HIGHLY ENANTIOSELECTIVE PROTONATION OF THIOL ESTER ENOLATES

Authors
FEHR C STEMPF I GALINDO J
Citation
C. Fehr et al., HIGHLY ENANTIOSELECTIVE PROTONATION OF THIOL ESTER ENOLATES, Angewandte Chemie, International Edition in English, 32(7), 1993, pp. 1042-1044
Citations number
34
Categorie Soggetti
Chemistry
Journal title
Angewandte Chemie, International Edition in English → ACNP
ISSN journal
05700833
Volume
32
Issue
7
Year of publication
1993
Pages
1042 - 1044
Database
ISI
SICI code
0570-0833(1993)32:7<1042:HEPOTE>2.0.ZU;2-I
Abstract
Impressive enantiomer excesses of 99% were achieved in the protonation of thioester enolate 2, prepared from racemic 1, with the chiral prot on sources (-)- and (+)-N-isopropylephedrine ((-)-3 and (+)-3). This l arge-scale procedure allows access to many enantiopure terpenoids.