CRANIAL MRI FINDINGS IN MYOTONIC-DYSTROPHY

MRI was performed in 13 patients with the adult form of myotonic dystr ophy (MD) and compared with that of sex- and age-matched normal contro ls. There was some cerebral atrophy in the patients and marked thicken ing of the skull in three of them, associated with ossification of the falx cerebri in two. We found high-signal areas on T2-weighted images in the white matter in 9 (70 %) of the patients; five showed high-sig nal areas in the subcortical white matter of the temporal lobes. These findings were associated with intellectual impairment in only one pat ient. who had a history of a difficult birth and temporal lobe epileps y.