A PRACTICAL SYNTHESIS OF THE ANTIBIOTIC TOYOCAMYCIN

Authors
SHARMA M BLOCH A BOBEK M
Citation
M. Sharma et al., A PRACTICAL SYNTHESIS OF THE ANTIBIOTIC TOYOCAMYCIN, Nucleosides & nucleotides, 12(6), 1993, pp. 643-648
Citations number
6
Categorie Soggetti
Biology
Journal title
Nucleosides & nucleotides → ACNP
ISSN journal
07328311
Volume
12
Issue
6
Year of publication
1993
Pages
643 - 648
Database
ISI
SICI code
0732-8311(1993)12:6<643:APSOTA>2.0.ZU;2-F
Abstract
The nucleoside antibiotic toyocamycin was synthesized by condensation of the silylated 4-amino-6-bromo-5-cyanopyrrolo2,3-d!pyrimidine with 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose, followed by debrominati on and deblocking.