Background. The purpose of this study was to prospectively compare the
effect of laparoscopic cholecystectomy (LC) versus open cholecystecto
my (OC) on postoperative pulmonary function. Methods. Forty consecutiv
e patients (20 in each group) who were evenly matched in terms of pulm
onary risk factors were assigned to either elective LC or OC. Pulmonar
y function studies, oxygen saturation, and chest radiography were perf
ormed on both groups before and after the operation until baseline lev
els were reached. Narcotic requirements and pulmonary complications we
re compared. The t test, ANOVA, and chi-squared analysis were used. Re
sults. Compared to the patients who underwent OC, patients who underwe
nt LC had a significant reduction in postoperative pulmonary impairmen
t (30% to 38%) in all areas studied including forced vital capacity; f
orced expiratory volume in 1 second; forced expiratory flow, mid-expir
atory phase; maximum forced expiratory flow; maximum voluntary ventila
tion; total lung capacity; and oxygen saturation. Pulmonary function r
eturned to baseline levels 4 to 10 days sooner after LC. Pulmonary com
plications including atelectasis and hypoxia were less frequent after
LC. An eight-fold decrease was noted in postoperative pain medication
requirement in the LC group. Conclusions. Compared to OC, laparoscopic
cholecystectomy results in a significantly reduced compromise in pulm
onary function and narcotic requirement leading to fewer postoperative
pulmonary complications. Laparoscopic cholecystectomy should be consi
dered the procedure of choice for elective cholecystectomy.