IMMUNOADSORPTION PLASMAPHERESIS FOR SEVERE GENERALIZED MYASTHENIA-GRAVIS

Two patients with severe generalised myasthenia gravis of childhood we re successfully treated with immunoadsorption plasmapheresis. One pati ent was a 5 year old girl and the other was a 12 year old girl. A dram atic improvement in bulbar symptoms and generalised muscle weakness wa s achieved without any side effects. Plasma exchange may also yield cl inical improvement for myasthenia gravis, but the treatment is accompa nied by the risk of viral infections and hypersensitivity reactions. I mmunoadsorption plasmapheresis is an effective treatment for severe ge neralised myasthenia gravis of childhood and is superior to plasma exc hange with respect to safety.