In a retrospective study 56 consecutive patients with uveitis of unkno
wn origin and 56 consecutive patients suffering from uveitis of establ
ished aetiology were investigated. The purpose of this study was to de
termine the frequency of positive serological tests for Lyme borrelios
is among patients with uveitis and to relate laboratory data to clinic
al findings. The antibody titre for Borrelia burgdorferi was determine
d by two assays: the indirect immunofluorescence assay and the enzyme
linked immunosorbent assay. A positive result according to one or both
assays was found for eight patients with uveitis of unknown aetiology
(14%) and three patients with uveitis of established cause (5%). On c
linical examination, none of the patients fulfilled the CDC criteria f
or diagnosis of Lyme borreliosis.