CLEAR-CELL ODONTOGENIC CARCINOMA WITH LYMPH-NODE METASTASIS

Clear cell odontogenic tumors are rare. Review of the literature showe d 9 cases with a prominent clear cell component. These lesions have ex hibited an aggressive behavior characterized by an infiltrative local growth pattern, recurrence, or metastases. We report a case of an odon togenic tumor that exhibited a biphasic pattern and was characterized by lymph node involvement identical histologically to the primary tumo r. We conclude that the presence of a clear cell component in an amelo blastomatous tumor should be viewed as a sign of de-differentiation, a nd that a malignancy with or without metastases should be considered a nd ruled out in such cases.