A 36 year old woman was admitted to our hospital for treatment of a hi
ghgrade rectal stenosis of unknown origin. She had a history of migrai
ne going back 10 years. On intensive questioning she admitted using up
to 5 ergotamine-containing suppositories a day. On the basis of histo
ry and clinical investigations the rectal stenosis must be connected w
ith the abuse of ergotamine-containing suppositories, This case demons
trates that patients with an unexplained rectal syndrome should be ask
ed for analgetics-containing suppositories specificly. Only discontinu
ation of treatment in time can preserve the patient from development o
f a rectal stenosis. In case of a rectal stenosis surgical treatment c
an be avoided by means of endoscopic controlled dilatation.