Implantation of coronary artery stents via the percutaneous femoral ap
proach is associated with a high rate of vascular complications at the
access site related to the size of the entry hole and the intense ant
icoagulation required to prevent stent thrombosis. Therefore we studie
d the feasibility of using the left brachial approach utilizing open a
rterial repair for implantation of coronary artery stents. Intracorona
ry stent implantation via the femoral approach in 24 patients (group A
) was compared with implantation via the brachial approach in 16 patie
nts (group B). Baseline lesion characteristics were similar in the two
groups. All stents in group A (n = 27 stents) were successfully deliv
ered to their target vessel. One stent in group B (n = 18 stents) coul
d not be delivered because of an inability to engage the coronary arte
ry from the brachial approach. There were no significant differences i
n the angiographic outcome between the two groups. Complications inclu
ding hematomas, hemorrhage requiring blood transfusion, vascular injur
y requiring surgery, and pseudoaneurysm formation were significantly m
ore common in group A than in group B (8/24 33%! versus 1/16 6%!, re
spectively; p < 0.05). In addition, the length of hospital stay was si
gnificantly longer for the femoral approach than the brachial approach
(9.4 vs 6.5 days, respectively; p < 0.05). Thus the left brachial app
roach for intracoronary stent implantation is technically feasible, sa
fe, and associated with fewer local vascular complications and a short
er hospitalization than the femoral approach.