Ys. Tuininga et al., ELECTROCARDIOGRAPHIC PATTERNS RELATIVE TO INITIATING MECHANISMS OF EXERCISE-INDUCED VENTRICULAR-TACHYCARDIA, The American heart journal, 126(2), 1993, pp. 359-367
The initiating mechanisms of exercise-induced ventricular tachycardia
were studied in a population of 5842 patients who performed 9064 bicyc
le exercise tests. Sixty (1%) patients had 194 episodes of ventricular
tachycardia during the test. Forty-two percent of these occurred duri
ng exercise and 58% during recovery. Two different initiating electroc
ardiographic patterns were observed. In 17 (28%) patients ventricular
tachycardia was initiated by a short-long-short sequence of R-R interv
als (group 1). Thirty-eight (63%) patients did not have this pattern o
f interval changes preceding ventricular tachycardia (group 2). Five (
8%) other patients showed both patterns. The clinical characteristics
of the groups were different for angina and cardiomyopathy but not for
previous myocardial infarction. In group 1 ventricular tachycardia wa
s related to recovery (76%; p < 0.05). In group 2 tachycardia occurren
ce was equally divided between exercise and recovery. The electrocardi
ographic differences suggest that different initiating mechanisms are
involved in the development of exercise-induced ventricular tachycardi
a. The present findings may enhance aimed drug therapy in ventricular
tachycardia.