A rare case of urethral flat wart caused by human papillomavirus (HPV)
type 16 was reported. A 34-year-old male consulted our department wit
h a complaint of urethral bleeding. A pair of symmetrical white flat w
arts combined with ulcer at the urethral meatus were found. Microscopi
c examination of the specimen demonstrated koilocytosis of the epithel
ium. In immunohistochemical study it was positive for HPV and HPV type
16 was detected by polymerase chain reaction.