EARLY MRI FINDINGS IN CREUTZFELDT-JAKOB-DISEASE

We describe the MRI changes preceding the onset of myoclonus in two pa tients whose post-mortem examination confirmed the diagnosis of Creutz feldt-Jakob disease (CJD). MRI showed changes in the striatum early in the course of CJD (2-6 months after the onset of apathy, interpreted as depression, and 1-2 months before the onset of further clinical sym ptoms). Only in one patient did electroencephalography record the typi cal triphasic sharp-waves, 1 month after MRI.