Se. Devries et al., CLINICAL AND PATHOLOGICAL FINDINGS OF BLUE-GREEN-ALGAE (MICROCYSTIS-AERUGINOSA) INTOXICATION IN A DOG, Journal of veterinary diagnostic investigation, 5(3), 1993, pp. 403-408
A healthy dog developed signs of lethargy and vomiting after ingesting
water from a tide pool containing blue-green algae. Fulminant hepatic
failure occurred, and the dog was euthanized 52 hours later. At necro
psy, the liver was large, friable, and discolored a dark red. Histopat
hology showed hepatocyte dissociation, degeneration, and necrosis. The
alp was identified as Microcystis aeruginosa, a known hepatotoxin. Th
e intraperitoneal administration of lyophilized cell material from the
bloom caused hepatic necrosis in mice.