A DITERPENE EPOXIDE FROM THE MARINE BROWN ALGA DICTYOTA SP - POSSIBLEVASOPRESSIN-V1 RECEPTOR ANTAGONIST

Authors
PATIL AD BERRY D BROOKS DP HEMLING ME KUMAR NV MITCHELL MP OHLSTEIN EH WESTLEY JW
Citation
Ad. Patil et al., A DITERPENE EPOXIDE FROM THE MARINE BROWN ALGA DICTYOTA SP - POSSIBLEVASOPRESSIN-V1 RECEPTOR ANTAGONIST, Phytochemistry, 33(5), 1993, pp. 1061-1064
Citations number
17
Categorie Soggetti
Plant Sciences
Journal title
Phytochemistry → ACNP
ISSN journal
00319422
Volume
33
Issue
5
Year of publication
1993
Pages
1061 - 1064
Database
ISI
SICI code
0031-9422(1993)33:5<1061:ADEFTM>2.0.ZU;2-Q
Abstract
A novel epoxide, in addition to eight known diterpenes, has been isola ted from a marine brown alga of the genus Dictyota. The structures of these compounds were established by the interpretation and comparison of spectral data with literature data. Most of the isolates demonstrat ed vasopressin receptor antagonist activity in vitro with the new epox ide being the most active of the diterpenes tested.