Patients with multiple injuries were studied retrospectively (n = 483,
ISS = 28 pts) and prospectively (n = 133, ISS = 42 pts) to determine
the significance of concomitant intraabdominal lesions in the manageme
nt and outcome of these subjects. In the retrospective part of the inv
estigation 134 patients with intra-abdominal trauma presented with sig
nificantly more severe injuries (ISS = 38) as compared to 349 subjects
with bland abdomen (ISS = 25). This resulted in a significantly diffe
rent mortality rate (27 vs 11 %). 119 patients with abdominal trauma w
ere managed operatively, with surgery instituted within 4 hrs after th
e accident in 104 cases. Delayed abdominal surgery was performed in 18
patients due to complications from the initial laparotomy and in 15 c
ases because of delayed diagnosis. Delayed operations resulted in an i
ncreased rate of local complications (33 vs. 6 % ). In the prospective
part of the study 33 out of 133 patients succumbed during resuscitati
on. In 14 of these, intractable bleeding from abdominal lesions was id
entified as the cause. In the 100 primary survivors, there was found n
o difference between 41 patients with and 59 patients without abdomina
l pathology with respect to injury severity, mortality, complications,
initial hemodynamic parameters or the secondary release of inflammato
ry mediators. However, the initial requirement for red blood cell subs
titution was significantly higher in subjects with intra-abdominal tra
uma. Our results demonstrate that massive intra-abdominal hemorrhage m
ay cause early mortality. In primary survivors, abdominal lesions have
not shown to be of prognostic relevance, provided that early resuscit
ation, early diagnosis and early operative therapy can be instituted.