Im. Leitman et al., THE EVALUATION AND MANAGEMENT OF KNOWN OR SUSPECTED STONES OF THE COMMON BILE-DUCT IN THE ERA OF MINIMAL ACCESS SURGERY, Surgery, gynecology & obstetrics, 176(6), 1993, pp. 527-533
Laparoscopic cholecystectomy (LC) has rapidly become the procedure of
choice for symptomatic cholelithiasis. The perioperative diagnosis and
modern treatment of suspected stones of the common bile duct (CBD) re
mains controversial. A database of 573 patients undergoing LC was comp
iled during an 11 month period. Sixty-seven patients (47 females, 20 m
ales) (13 percent) were suspected of having CBD stones based upon clin
ical, laboratory and roentgenographic evidence. Fifty-two patients und
erwent endoscopic retrograde cholangiopancreatography (ERCP) (45 preop
erative and seven postoperative). Seventeen patients were studied with
intraoperative cholangiogram (IOC). The indications for cholangiograp
hy (either ERCP or IOC) included pancreatitis (group 1), clinical hist
ory suggestive of CBD stones, but normal preoperative liver function t
ests (LFT) (group 2), cholangitis (group 3), grossly abnormal LFT (gro
up 4) and dilated CBD (greater than 7 millimeters on sonogram) (group
5). The incidence of CBD stones was three of 14 (21 percent) in group
1, six of 20 (30 percent) in group 2, two of three (67 percent) in gro
up 3, 16 of 26 (62 percent) in group 4 and two of four (50 percent) in
group 5. Overall, 29 patients (23 females and six males) had stones r
etrieved from the CBD. Of the 52 ERCP, 20 endoscopic sphincterotomies
were performed for documented CBD stones. Of the group that had pre-LC
ERCP, three (6 percent) ultimately required an open procedure. There
were three instances of post-ERCP pancreatitis (6 percent) and ERCP wa
s not able to opacify or clear the CBD in four instances. Seven patien
ts had postoperative ERCP with successful retrieval of retained CBD st
ones (100 percent). Of the 17 IOC, eight were positive-two patients un
derwent laparoscopic clearance of the CBD and six required conversion
to an open procedure. There were no deaths or extensive complications.
Total and direct bilirubin, alkaline phosphatase and serum glutamic p
yruvic transaminase were independently related to the presence of a CB
D stone, while demographic data, past medical history, preoperative sy
mptoms, leukocyte count, vital signs, amylase, serum glutamic-oxalacet
ic transaminase nuclear scintigraphic visualization of the duodenum or
size of CBD on sonography, were not. No patient with biliary pancreat
itis had CBD stones without abnormalities in the LFT or the preoperati
ve sonogram. ERCP is a useful technique to clear the CBD pre-LC. Howev
er, ERCP in patients with biliary pancreatitis, but otherwise normal p
reoperative tests, has a low yield. In this group of patients, IOC is
an appropriate alternative to pre-LC ERCP.