APPROACHES TO IDENTIFY GENES INVOLVED IN DROSOPHILA EMBRYONIC CNS DEVELOPMENT

Citation
E. Noll et al., APPROACHES TO IDENTIFY GENES INVOLVED IN DROSOPHILA EMBRYONIC CNS DEVELOPMENT, Journal of neurobiology, 24(6), 1993, pp. 701-722
Citations number
115
Categorie Soggetti
Neurosciences
Journal title
ISSN journal
00223034
Volume
24
Issue
6
Year of publication
1993
Pages
701 - 722
Database
ISI
SICI code
0022-3034(1993)24:6<701:ATIGII>2.0.ZU;2-Q
Abstract
Many of the steps involved in formation of the Drosophila embryonic ce ntral nervous system (CNS) have been identified by both descriptive an d experimental studies. In this review we will describe the various ap proaches that have been used to identify molecules involved in CNS dev elopment and the advantages and disadvantages of each of them. Our dis cussion will by no means be exhaustive; but rather we will discuss our experiences with each approach and provide an overview of what has be en learned by using these methodologies. Finally, we will discuss meth ods that have been recently developed and how they are likely to provi de further insight into CNS development.