Six patients with extreme short bowel syndrome (4.2 +/- 4.9 cm of resi
dual small bowel) were provided home parenteral nutrition (HPN) for 14
,397 days. The average age at onset of HPN was 38 years (18-64 years).
Patients maintained body weight at 97% of ideal (86-112%) with mean s
erum albumin of 3.7 +/- 0.6 g/dL (normal 3.5-5.8 g/dL), serum transfer
rin of 341 +/- 104 mg/dL (normal 200-400 mg/dL), and mean serum pre-al
bumin of 27.5 +/- 12.6) mg/dL (normal 16.6-43 mg/dL). Hospital admissi
on for HPN-related complications was required 10.3 times/patient for a
total of 864 hospital days and was catheter related in 71% of episode
s. Catheter sepsis occurred once per 436 catheter days and required ca
theter removal in only 33% of instances. Five patients were able to re
sume an oral diet, five had returned to work or school, and three were
married with family. HPN allowed return to a quality productive life
with acceptable morbidity following catastrophic massive bowel resecti
on.