PATHOPHYSIOLOGICAL MECHANISMS OF THE CARD IORESPIRATORY SYSTEM FUNCTION DISORDER IN CHILDREN OF MID-SCHOOL AGE WITH CHRONIC OBSTRUCTIVE PULMONARY-DISEASES

The basic indices of the cardiorespiratory system function, ps exchang e, regional pulmonary functions have been studied. It is stated that a group of children with a higher level of oxygen consumption (hypererg ic type) as against a control group is characterized by disorder in pe rmeability of terminal branches of a bronchial tree, by the developmen t of acute obstructive emphysema, increase in alveolar ventilation wit h relative decrease in minute blood volume, arterial hypoxemia with po ssible emergence of tissue hypoxia. A decrease in permeability of larg e bronchi were observed in a group of children with a low level of oxy gen consumption (hypoergic type). Due to this decrease the hypoventila tion zones appeared. It caused the development of arterial hypoxemia, but a risk of the tissue hypoxia emergence was insignificant.