USE OF RESPIRATORY MIXTURE CONTAINING 8.0 -8.5-PERCENT OF OXYGEN IN HYPOXYRADIOTHERAPY OF CERVICAL CARCINOMAS

Citation
T. Tachev et al., USE OF RESPIRATORY MIXTURE CONTAINING 8.0 -8.5-PERCENT OF OXYGEN IN HYPOXYRADIOTHERAPY OF CERVICAL CARCINOMAS, Fiziologiceskij zurnal, 38(5), 1992, pp. 64-67
Citations number
5
Categorie Soggetti
Physiology
Journal title
ISSN journal
02018489
Volume
38
Issue
5
Year of publication
1992
Pages
64 - 67
Database
ISI
SICI code
0201-8489(1992)38:5<64:UORMC8>2.0.ZU;2-2
Abstract
Combined radiotherapy of patients with cervical carcinoma of stages II b and IIIb was conducted. Hypoxia (8.0-8.5 % of O2 in the respiratory mixture) was used in microfractionated (2 Gy) irradiation of metastati c spreading zones. When irradiating under conditions of hypoxia, the n umber of fracions was brought up to 28 as compared to 20 in control. D espite a 40 %-increase of the dose, seriousness of radiation reactions and remote injuries remained al the same level. It is found that pati ents endure well the respiratory mixture for 6 min. necessary for irra diation.