Ma. Aller et al., AUXILIARY LIVER-TRANSPLANTATION IN THE PIG WITHOUT PORTAL BLOOD - A STUDY OF A NEW TECHNIQUE FOR APPLICATION TO THE HETEROTOPIC HEPATIC XENOTRANSPLANT, International surgery, 78(2), 1993, pp. 117-120
An auxiliary liver transplantation surgical technique in the pig, in w
hich the graft only receives blood flow via the hepatic artery since a
n end-to-side portacaval shunt is performed in the donor animal prior
to the transplantation, is described. The functional impairment of the
receptor liver was done by a ligature of the choledoch, provoking dea
th by sepsis in six of the transplanted animals at 8.16 +/- 6.61 days
post transplantation. The auxiliary liver never suffered atrophy and p
revented jaundice. It can be concluded that this simple surgical techn
ique could be applied to the heterotopic xenotransplantation when the
complications inherent in the immunological aggression are eliminated.