ELEVATED GROWTH-HORMONE RESPONSES TO PYRIDOSTIGMINE IN OBSESSIVE-COMPULSIVE DISORDER - EVIDENCE OF CHOLINERGIC SUPERSENSITIVITY

Authors
LUCEY JV BUTCHER G CLARE AW DINAN TG
Citation
Jv. Lucey et al., ELEVATED GROWTH-HORMONE RESPONSES TO PYRIDOSTIGMINE IN OBSESSIVE-COMPULSIVE DISORDER - EVIDENCE OF CHOLINERGIC SUPERSENSITIVITY, The American journal of psychiatry, 150(6), 1993, pp. 961-962
Citations number
8
Categorie Soggetti
Psychiatry,Psychiatry
Journal title
The American journal of psychiatry → ACNP
ISSN journal
0002953X
Volume
150
Issue
6
Year of publication
1993
Pages
961 - 962
Database
ISI
SICI code
0002-953X(1993)150:6<961:EGRTPI>2.0.ZU;2-#
Abstract
The growth hormone response to the acetylcholinesterase inhibitor pyri dostigmine was measured in nine normothymic outpatients who met DSM-II I-R criteria for obsessive-compulsive disorder. The responses were sig nificantly elevated when compared to those found in a healthy comparis on group (N=9). The data suggest that cholinergic supersensitivity is present in obsessive-compulsive disorder.