PROPYL-BIS[2-(TRIMETHYLSILYL)ETHYL]PHOSPHORAMIDITE - AN ATTRACTIVE PHOSPHITYLATING AGENT COMPATIBLE WITH THE FMOC T-BUTYL STRATEGY FOR THE SYNTHESIS OF PHOSPHOTYROSINE-CONTAINING PEPTIDES/

Authors
CHAO HG BERNATOWICZ MS KLIMAS CE MATSUEDA GR
Citation
Hg. Chao et al., PROPYL-BIS[2-(TRIMETHYLSILYL)ETHYL]PHOSPHORAMIDITE - AN ATTRACTIVE PHOSPHITYLATING AGENT COMPATIBLE WITH THE FMOC T-BUTYL STRATEGY FOR THE SYNTHESIS OF PHOSPHOTYROSINE-CONTAINING PEPTIDES/, Tetrahedron letters, 34(21), 1993, pp. 3377-3380
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
21
Year of publication
1993
Pages
3377 - 3380
Database
ISI
SICI code
0040-4039(1993)34:21<3377:P-AAP>2.0.ZU;2-K
Abstract
A new phosphitylating agent, compatible with the Fmoc/t-butyl strategy for the production of phosphotyrosine containing peptides was synthes ized. Our results demonstrated that high yields and high purities of p hosphotyrosine peptides can be obtained using this phosphitylating age nt.