THE TOTAL SYNTHESIS OF RITIPENEMS - CONSTRUCTION OF PENEM THIAZOLINE RING BY INCORPORATION OF 2 2C UNITS OF GLYCOLIC ACID

Authors
CABRI W ZARINI F DANELLO M MARCHI M BEDESCHI A FRANCESCHI G
Citation
W. Cabri et al., THE TOTAL SYNTHESIS OF RITIPENEMS - CONSTRUCTION OF PENEM THIAZOLINE RING BY INCORPORATION OF 2 2C UNITS OF GLYCOLIC ACID, Tetrahedron letters, 34(21), 1993, pp. 3491-3492
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
21
Year of publication
1993
Pages
3491 - 3492
Database
ISI
SICI code
0040-4039(1993)34:21<3491:TTSOR->2.0.ZU;2-H
Abstract
Short syntheses of Ritipenem Acoxyl 1a and Ritipenem 1b are reported. The syntheses start from R)-1-(t-butyldimethylsilyloxy)ethyl]azetidin- 2-one 3 and are based on the incorporation of two 2C units obtained by manipulation of glicolyc acid 4.