N-15 NMR-STUDIES OF THE BINDING OF C-15N(-) WITH GOLD(I) DRUGS

Authors
ISAB AA GHAZI IH WAZEER MIM PERZANOWSKI HP
Citation
Aa. Isab et al., N-15 NMR-STUDIES OF THE BINDING OF C-15N(-) WITH GOLD(I) DRUGS, Journal of inorganic biochemistry, 50(4), 1993, pp. 299-304
Citations number
24
Categorie Soggetti
Biology,"Chemistry Inorganic & Nuclear
Journal title
Journal of inorganic biochemistry → ACNP
ISSN journal
01620134
Volume
50
Issue
4
Year of publication
1993
Pages
299 - 304
Database
ISI
SICI code
0162-0134(1993)50:4<299:NNOTBO>2.0.ZU;2-H
Abstract
N-15 NMR studies of the interaction of N-15 cyanide ion with gold(I)-t hiomalate (Autm) and gold(I)-thioglucose (Autg) have been carried out at pH 7.40. The chemical shifts of the two N-15 ions containing speci es (Au(CN)2-)-N-15 and (RS-Au-CN-)-N-15 (where RS- = tm- or tg-)were i dentified at 265.94 and 260.30 ppm, respectively. From the broadened N -15 NMR signals, approximate life times of the RS-Au-CN- species were calculated.