Pharmacoepidemiology has become an important tool for identifying patt
erns of drug use and adverse drug reactions in the general population.
Drug data bases derived from population-based samples have been parti
cularly useful in addressing questions such as adherence to national g
uidelines for the treatment of chronic diseases. As part of the Pawtuc
ket Heart Health Program, a continuing community-based research and de
monstration project, detailed information regarding the use of drugs a
mong the general population of two southeastern New England cities was
collected using cross-sectional and longitudinal methodologies.