It has been suggested that certain artifacts in blood pressure measure
ment by auscultation stem from stiffness of the tissues underneath the
pressure cuff, resulting in a component of cuff pressure being requir
ed to overcome resistance to brachial artery collapse. This paper desc
ribes a technique for measuring the pressure required to collapse a se
gment of the brachial artery which has been isolated from central arte
rial pressure. This measurement is termed the arterial closing pressur
e. In a study of eleven elderly subjects, the artery collapsed spontan
eously (zero closing pressure) after being isolated from central press
ure in seven subjects. The remaining four required external pressures
ranging from 4.6 to 10.7 kPa (35 to 81 mmHg) in order to collapse the
artery. Thus arterial closing pressure may frequently be a significant
fraction of arterial blood pressure in the elderly population, and ma
y contribute an error in the measurement of blood pressure by ausculta
tion. Arterial closing pressure may be a useful tool for investigating
the origin of differences between indirect and direct blood pressure
measurements, and also in the investigation of spontaneous arterial cl
osure.