AQUAGENIC PRURITUS ASSOCIATED WITH JUVENILE XANTHOGRANULOMA

While the relationship of aquagenic pruritus (AP) to haematoproliferat ive conditions is well-recognized, an association with histiocytic dis orders has not previously been described. The case of a child with bot h AP and juvenile xanthogranulomata (JXG) is reported. The cutaneous l esions were typical of JXG, both clinically and histologically, and in addition there were radiological changes consistent with JXG in the l ungs. AP is rare in childhood and the coincidental occurrence with unu sually extensive JXG seems unlikely.