Methyl esters of hydroxycinnamic acids are photobiologically active. C
is(Z) and trans(E) p-methoxymethylcinnamate photosensitize Escherichia
coli and Chinese hamster ovary cells. They also produce sister chroma
tid exchanges. Photosensitization is oxygen independent, and the cinna
mates are not genetically active in the absence of light in the Ames S
almonella typhimurium test.