ATTEMPTED SYNTHESIS OF SUBSTITUTED 8-OXO-4-OXA-1-AZABICYCLO[3,3,0]OCTANE THROUGH INTRAMOLECULAR REDUCTIVE CYCLIZATION

Citation
Sk. Mishra et al., ATTEMPTED SYNTHESIS OF SUBSTITUTED 8-OXO-4-OXA-1-AZABICYCLO[3,3,0]OCTANE THROUGH INTRAMOLECULAR REDUCTIVE CYCLIZATION, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 32(6), 1993, pp. 641-644
Citations number
7
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
03764699
Volume
32
Issue
6
Year of publication
1993
Pages
641 - 644
Database
ISI
SICI code
0376-4699(1993)32:6<641:ASOS8>2.0.ZU;2-U
Abstract
Reductive intramolecular cyclisation of 2-(N-succinimido)-1-ethanol gi ves 8-oxo-4-oxa-1-aza-bicyclo[3,3,0]octane in a good yield. On introdu ction of further substitution of C-1 and C-2 no cyclisation is observe d. A mechanistic rational is presented.