PREPARATION OF CYCLODEXTRIN PRECIPITATES WITH VOLATILE HYDROCARBONS IN AQUEOUS-MEDIA, AND DETERMINATION OF HYDROCARBON CYCLODEXTRIN MOLAR RATIOS IN THE PRECIPITATES
I. Sanemasa et al., PREPARATION OF CYCLODEXTRIN PRECIPITATES WITH VOLATILE HYDROCARBONS IN AQUEOUS-MEDIA, AND DETERMINATION OF HYDROCARBON CYCLODEXTRIN MOLAR RATIOS IN THE PRECIPITATES, Bulletin of the Chemical Society of Japan, 66(5), 1993, pp. 1424-1429
A technique is proposed to prepare cyclodextrin (CyD) precipitates wit
h volatile hydrocarbons. On introducing the vapor of a liquid or solid
hydrocarbon into alpha-, beta-, or gamma-CyD in an aqueous solution a
nd circulating it in a closed system, CyD can be easily precipitated.
The CyD precipitates isolated from aqueous solutions were analyzed for
the hydrocarbon/CyD molar ratio. The concentration of CyD in the supe
rnatant aqueous solution was also measured. The technique has been app
lied at 25-degrees-C to such hydrocarbons as n-alkanes (C5 to C10), cy
clohexane, halobenzenes(fluoro-, chloro-, bromo-, and iodo-benzene), p
-difluorobenzene, benzene, naphthalene, biphenyl, and diphenylmethane.
Precipitates were also prepared in beta-CyD solutions with the vapor
of C5-Cg mixtures at various mixing ratios.