ENDOMETRIAL CANCER METASTASIS TO BRAIN - REPORT OF 2 CASES AND A REVIEW OF THE LITERATURE

Two cases of brain metastases from endometrial adenocarcinoma are repo rted. A 70-year-old female presented with lung metastases 14 months af ter hysterectomy and adjuvant treatment. At 6 months later, a cerebell ar metastasis was resected and followed by radiation therapy. The pati ent died 5.5 months later. In the second case, a 60-yearold patient de veloped a lung endometrial metastasis 6 years after initial treatment. At 1 year later she was diagnosed with bilateral hydrocephalus caused by a left temporal and posterior fossa tumor. A ventriculoperitoneal shunt was inserted and she received brain radiation. Two weeks later s he gradually became comatose, with right hemiparesis. A metastatic, he morrhagic temporal tumor was resected but the patient never regained c onsciousness and died after 7 weeks. The existing literature on brain metastases from endometrial adenocarcinoma is reviewed.