C-16 HYDROXYLATED ABIETANE DITERPENES FROM SALVIA-MELLIFERA - ABSOLUTE-CONFIGURATION AND BIOGENETIC IMPLICATIONS

Authors
LUIS JG ANDRES LS PERALES A
Citation
Jg. Luis et al., C-16 HYDROXYLATED ABIETANE DITERPENES FROM SALVIA-MELLIFERA - ABSOLUTE-CONFIGURATION AND BIOGENETIC IMPLICATIONS, Tetrahedron, 49(22), 1993, pp. 4993-5000
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
49
Issue
22
Year of publication
1993
Pages
4993 - 5000
Database
ISI
SICI code
0040-4020(1993)49:22<4993:CHADFS>2.0.ZU;2-0
Abstract
Two new C-16 hydroxylated abietane diterpenes and the known compounds cryptotanshinone and isopimaradiene have now been isolated from Salvia mellifera and identified by rigorous spectroscopic and X-ray crystall ographic analyses. Our findings indicate that epoxidation of the monos ubstituted double bond of an isopimaradiene precursor must take place before 16-hydroxylated abietanes are formed.