Ar. Carroll et al., STUDIES OF AUSTRALIAN ASCIDIANS .2. NOVEL CYTOTOXIC IODOTYROSINE-BASED ALKALOIDS FROM COLONIAL ASCIDIANS, APLIDIUM SP, Australian Journal of Chemistry, 46(6), 1993, pp. 825-832
Samples of colonial ascidians, Aplidium sp., have yielded three novel
iodinated L-tyrosine alkaloids (1)-(3). The structures of these compou
nds were delineated on the basis of one-and two-dimensional n.m.r. exp
eriments at 300 MHz, and confirmed by the total synthesis of one of th
em (2).