Ma. Miller et al., TESTOSTERONE REGULATES GALANIN GENE-EXPRESSION IN THE BED NUCLEUS OF THE STRIA TERMINALIS, Brain research, 611(2), 1993, pp. 338-341
The regulation of galanin (GAL) gene expression in the bed nucleus of
the stria terminalis (BNST) by testosterone (T) was investigated using
in situ hybridization histochemistry. Castration of adult male rats s
ignificantly reduced both the number of cells which expressed GAL mRNA
and the average number of grains per cell. These effects were reverse
d by testosterone treatment. Testosterone stimulates GAL gene expressi
on in the same neurons that have previously been shown to exhibit ster
oid regulation of vasopressin gene expression.