THE EFFECT OF PARTICLE-SIZE ON THE HEAT OF IMMERSION OF MICROCRYSTALLINE CELLULOSE

Authors
ROWE RC PARKER MD MCKILLOP AG
Citation
Rc. Rowe et al., THE EFFECT OF PARTICLE-SIZE ON THE HEAT OF IMMERSION OF MICROCRYSTALLINE CELLULOSE, International journal of pharmaceutics, 91(2-3), 1993, pp. 247-250
Citations number
16
Categorie Soggetti
Pharmacology & Pharmacy
Journal title
International journal of pharmaceutics → ACNP
ISSN journal
03785173
Volume
91
Issue
2-3
Year of publication
1993
Pages
247 - 250
Database
ISI
SICI code
0378-5173(1993)91:2-3<247:TEOPOT>2.0.ZU;2-E
Abstract
The effect of particle size on the heat of immersion of microcrystalli ne cellulose (Avicel) has been measured using microcalorimetry. Curves of heat of immersion against moisture content for all four particle s izes were superimposable when the data were expressed on a weight basi s but when expressed on a surface area basis, the data for the smalles t particle size were consistently lower. Reasons for this anomaly have been hypothesised.