PI-220, A NEW PLATELET-AGGREGATION INHIBITOR

Authors
KAGAMIZONO T KAWASHIMA A KISHIMURA Y YAMAGISHI M TSUCHIDA Y KONDO H HANADA K
Citation
T. Kagamizono et al., PI-220, A NEW PLATELET-AGGREGATION INHIBITOR, Bioscience, biotechnology, and biochemistry, 57(5), 1993, pp. 766-769
Citations number
5
Categorie Soggetti
Biology,Agriculture,"Biothechnology & Applied Migrobiology","Food Science & Tenology
Journal title
Bioscience, biotechnology, and biochemistry → ACNP
ISSN journal
09168451
Volume
57
Issue
5
Year of publication
1993
Pages
766 - 769
Database
ISI
SICI code
0916-8451(1993)57:5<766:PANPI>2.0.ZU;2-O
Abstract
PI-220 was found in a culture broth of Streptomyces sp. A8059, which h ad been isolated from a soil sample collected in Okinawa Prefecture, J apan. PI-220 inhibited aggregation of rabbit platelets with an IC50 va lue of 1.0-2.1 x 10(-3)M.