STRUCTURE OF MALFORMIN-B, A PHYTOTOXIC METABOLITE PRODUCED BY ASPERGILLUS-NIGER

Authors
KIM KW SUGAWARA F YOSHIDA S MUROFUSHI N TAKAHASHI N CURTIS RW
Citation
Kw. Kim et al., STRUCTURE OF MALFORMIN-B, A PHYTOTOXIC METABOLITE PRODUCED BY ASPERGILLUS-NIGER, Bioscience, biotechnology, and biochemistry, 57(5), 1993, pp. 787-791
Citations number
13
Categorie Soggetti
Biology,Agriculture,"Biothechnology & Applied Migrobiology","Food Science & Tenology
Journal title
Bioscience, biotechnology, and biochemistry → ACNP
ISSN journal
09168451
Volume
57
Issue
5
Year of publication
1993
Pages
787 - 791
Database
ISI
SICI code
0916-8451(1993)57:5<787:SOMAPM>2.0.ZU;2-S
Abstract
Malformin B, produced by Aspergillus niger, was separated into six com pounds by HPLC. Their structures were determined by amino acid analyse s, and by mass spectral and two-dimensional NMR experiments to be cycl ic pentapeptides structurally related to malformin A1. Both the NMR an d MS/MS experiments suggest cyclo-D-cysteinyl-D-cysteinyl-L-amino acid -D-amino acid-L-amino acid as the essential structure of malformins.