EVALUATION OF A NEW POLAR ORGANIC HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC MOBILE PHASE FOR CYCLODEXTRIN-BONDED CHIRAL STATIONARY PHASES

Authors
CHANG SC REID GL CHEN S CHANG CD ARMSTRONG DW
Citation
Sc. Chang et al., EVALUATION OF A NEW POLAR ORGANIC HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC MOBILE PHASE FOR CYCLODEXTRIN-BONDED CHIRAL STATIONARY PHASES, TrAC. Trends in analytical chemistry, 12(4), 1993, pp. 144-153
Citations number
15
Categorie Soggetti
Chemistry Analytical
Journal title
TrAC. Trends in analytical chemistry → ACNP
ISSN journal
01659936
Volume
12
Issue
4
Year of publication
1993
Pages
144 - 153
Database
ISI
SICI code
0165-9936(1993)12:4<144:EOANPO>2.0.ZU;2-Q
Abstract
A polar-organic mobile phase system composed of acetonitrile, with sma ll portions of hydrogen bonding modifiers, was developed for the enant iomeric separation of chiral molecules on cyclodextrin-bonded phases. This mobile phase mode allows for the separation of a wide variety of analytes which cannot be resolved in either traditional normal- or rev ersed-phase modes on cyclodextrin-bonded phases.