Jjn. Ngeranwa et al., PATHOGENESIS OF TRYPANOSOMA (BRUCEI) EVANSI IN SMALL EAST-AFRICAN GOATS, Research in Veterinary Science, 54(3), 1993, pp. 283-289
Trypanosoma evansi is the cause of surra, a camel disease which is the
most important single cause of economic losses in camel rearing areas
. Sheep and goats herded with camels are the most likely hosts for T e
vansi. Upon intravenous infections goats developed erratic parasitaemi
a, lost weight and their packed cell volume dropped significantly (P<0
.001). Trypanosomes were demonstrated by direct microscopy in extravas
cular locations such as synovial, peritoneal and cerebrospinal fluids
and also in lymph by subinoculations into mice. The carcases were emac
iated and pale. Histologically there was lymphatic tissue hyperplasia,
muscular atrophy and nephrotic changes. Two animals had necrotic foci
in the liver, kidneys, lymph nodes, spleen and lungs and also broncho
pneumonia. Histologically there was depopulation of lymphocytes in lym
phatic tissues, destruction of hepatocytes in the liver with infiltrat
ion by inflammatory cells in the liver, lymph nodes, spleen and the ki
dneys.