Focusing of heavy-ion beams on an indirectly driven inertial fusion ta
rget can be achieved, in principle, under vacuum conditions in the rea
ctor chamber. Due to performance limitations in the storage rings of t
he driver accelerator, a relatively large number of small emittance be
ams is required. We suggest that the effect of space charge can be des
cribed in terms of three distinct mechanisms: an increase of the entra
nce divergence angle; a current sensitivity of the focal spot; and the
effect of a nonuniform distribution. The first two can be calculated
by means of an envelope model. The resulting current sensitivity formu
la is confirmed by a computer simulation taking into account the corre
ct Coulomb forces between interacting beamlets. We find that for propa
gation in vacuum the current sensitivity is considerable, in particula
r for charge states Z > 1, since the spot size blow-up scales like Z4/
A2. The effect depends on the total current in a bundle-and not the nu
mber of beamlets in it-and thus determines how many bundles have to be
used. Possible cures are briefly discussed.