HEMODYNAMIC-EFFECTS AND ADVERSE-EFFECTS O F THE ANTIARRHYTHMIC DRUG AWD-G256 IN MAN

Authors
VOLKMANN H DANNBERG G KUHNERT H HOFFMANN A MARSCHNER JP REIMANN I FARKER K
Citation
H. Volkmann et al., HEMODYNAMIC-EFFECTS AND ADVERSE-EFFECTS O F THE ANTIARRHYTHMIC DRUG AWD-G256 IN MAN, Die Pharmazie, 48(5), 1993, pp. 385-387
Citations number
4
Categorie Soggetti
Pharmacology & Pharmacy",Chemistry
Journal title
Die Pharmazie → ACNP
ISSN journal
00317144
Volume
48
Issue
5
Year of publication
1993
Pages
385 - 387
Database
ISI
SICI code
0031-7144(1993)48:5<385:HAAOFT>2.0.ZU;2-K
Abstract
In 19 patients with different supraventricular tachycardias the antiar rhythmic drug AWD-G256 was studied to investigate the effects on hemod ynamic parameters. Over all, stroke volume, pulmonary pressure and sys temic blood pressure were not significantly altered. The only main adv erse effect was a transient rise of serum transaminases in two patient s. We conclude that AWD-G256 is usually hemodynamically tolerated, but the antiarrhythmically effective dosage is not reached yet.