K. Kumar et al., TRUE TRACER RADIOLABELING OF GADOLINIUM COMPLEX OF YDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE-1,4,7 TRIACETIC ACID (HP-DO3A), Journal of labelled compounds & radiopharmaceuticals, 33(6), 1993, pp. 473-482
True tracer radiolabeling, purification, and analysis of a gadolinium
complex of HP-DO3A (10- (2-hydroxy-propyl)- 1,4,7,10-tetraazacyclo dod
ecane-1,4,7-triacetic acid) was achieved by the reaction of carrier-ad
ded (GdCl3)-Gd-153 and excess free ligand. Two analytical methods (ITL
C and HPLC) were developed to determine the purity of radiolabeled sam
ples.