CHEMISTRY OF 1,3-DIOXEPINS .6. 6A-TETRAHYDRO-1H,4H-[1,3]-DIOXEPINO[5,6-B]AZIRINES - A NOVEL CLASS OF FUSED DIOXEPINS, POTENT HYPOGLYCEMIC AGENTS

Authors
DUMIC M FILIC D VINKOVIC M JAMNICKY B KAMENAR B
Citation
M. Dumic et al., CHEMISTRY OF 1,3-DIOXEPINS .6. 6A-TETRAHYDRO-1H,4H-[1,3]-DIOXEPINO[5,6-B]AZIRINES - A NOVEL CLASS OF FUSED DIOXEPINS, POTENT HYPOGLYCEMIC AGENTS, Tetrahedron letters, 34(22), 1993, pp. 3639-3642
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
34
Issue
22
Year of publication
1993
Pages
3639 - 3642
Database
ISI
SICI code
0040-4039(1993)34:22<3639:CO1.6>2.0.ZU;2-6
Abstract
The new hypoglycemics, 1-sulfonyl-dioxepinoazirines 2, derived from a novel heterocyclic system, 6a-tetrahydro-1H,4H-[1,3]-dioxepino[5,6-b]a zirine, have been synthesized starting from trans-6-acetylamino-5-chlo ro-1,3-dioxepanes 7 via azirines 3. Their structure has been confirmed by the single crystal X-ray diffraction of 1-(4-acetylaminobenzenesul fonyl) derivative 2b.