TCFL4 - A GENE AT 17Q21.1 ENCODING A PUTATIVE BASIC HELIX-LOOP-HELIX LEUCINE-ZIPPER TRANSCRIPTION FACTOR

Authors
BJERKNES M CHENG H
Citation
M. Bjerknes et H. Cheng, TCFL4 - A GENE AT 17Q21.1 ENCODING A PUTATIVE BASIC HELIX-LOOP-HELIX LEUCINE-ZIPPER TRANSCRIPTION FACTOR, Gene, 181(1-2), 1996, pp. 7-11
Citations number
16
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
181
Issue
1-2
Year of publication
1996
Pages
7 - 11
Database
ISI
SICI code
0378-1119(1996)181:1-2<7:T-AGA1>2.0.ZU;2-D
Abstract
TCFL4 (transcription factor like 4) is the HGMW-approved symbol for th e gene of a widely expressed putative basic helix-loop-helix leucine-z ipper (bHLH-zip) transcription factor which is located 3' to HSD17B1 ( 17-beta-hydroxysteroid dehydrogenase gene) at 17q21.1, centromeric to the BRCA1 (a gene implicated in familial breast cancer) locus. We repo rt the human gene structure and the murine cDNA sequence of two varian ts, about 1.5 and 2.2 kb in, size. The deduced protein is highly conse rved between mouse and man.