AZAMACROLIDES - A FAMILY OF ALKALOIDS FROM THE PUPAL DEFENSIVE SECRETION OF A LADYBIRD BEETLE (EPILACHNA-VARIVESTIS)

Authors
ATTYGALLE AB MCCORMICK KD BLANKESPOOR CL EISNER T MEINWALD J
Citation
Ab. Attygalle et al., AZAMACROLIDES - A FAMILY OF ALKALOIDS FROM THE PUPAL DEFENSIVE SECRETION OF A LADYBIRD BEETLE (EPILACHNA-VARIVESTIS), Proceedings of the National Academy of Sciences of the United Statesof America, 90(11), 1993, pp. 5204-5208
Citations number
22
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Proceedings of the National Academy of Sciences of the United Statesof America → ACNP
ISSN journal
00278424
Volume
90
Issue
11
Year of publication
1993
Pages
5204 - 5208
Database
ISI
SICI code
0027-8424(1993)90:11<5204:A-AFOA>2.0.ZU;2-A
Abstract
Defensive droplets from glandular hairs of the pupa of the Mexican bea n beetle, Epilachna varivestis, contain a group of structurally novel alkaloids, the azamacrolides. The major constituent of this secretion, epilachnene, is shown to be (5Z)-11-propyl-12-azacyclotetradec-5-en-1 4-olide. The secretion also contains an epilachnadiene and trace amoun ts of three closely related components.