CORRELATION BETWEEN DENSITOMETRIC AND HYSTOMORPHOMETRIC VALUES IN ISOLATED VERTEBRAE OF SPRAGUE-DAWLEY RATS

Authors
CAMPODARVE I DIEZ A PUIG J SERRANO S MARINOSO ML ARNAU MD CUCURULL J IBANEZ J NOGUES X AUBIA J
Citation
I. Campodarve et al., CORRELATION BETWEEN DENSITOMETRIC AND HYSTOMORPHOMETRIC VALUES IN ISOLATED VERTEBRAE OF SPRAGUE-DAWLEY RATS, Calcified tissue international, 52(6), 1993, pp. 470-471
Citations number
3
Categorie Soggetti
Endocrynology & Metabolism
Journal title
Calcified tissue international → ACNP
ISSN journal
0171967X
Volume
52
Issue
6
Year of publication
1993
Pages
470 - 471
Database
ISI
SICI code
0171-967X(1993)52:6<470:CBDAHV>2.0.ZU;2-6
Abstract
The study of bone mass in experimental animals usually requires invasi ve techniques. Dual energy X-ray absorptiometry (DEXA) may be an alter native as a non-invasive method (1). Bone mineral density (BMD) and bo ne mineral content (BMC) of 62 vertebrae of Sprague Dawley rats (SDr) measured by DEXA densitometry were compared with histomorphometric bon e volume measurements, and a statistically significant correlation was found (r = 0.79 and 0.75, respectively, p < 0.001). In conclusion, DE XA is an accurate and feasible technique for the study of trabecular b one mass in SDr.