H. Jousimiessomer et al., BACTERIOLOGICAL FINDINGS IN PERITONSILLAR ABSCESSES IN YOUNG-ADULTS, Clinical infectious diseases, 16, 1993, pp. 190000292-190000298
Aspirated pus samples from 124 patients with peritonsillar abscess wer
e Cultured quantitatively for aerobes and anaerobes. A total of 98% of
the samples yielded bacteria. Of the 550 isolates obtained (mean, 4.4
per patient), 143 were aerobes (representing 16 species or groups) an
d 407 were anaerobes (representing 40 species or groups). Aerobes were
isolated from 86% of patients-alone in 20 cases and together with ana
erobes in 87. The most common aerobic isolates were Streptococcus pyog
enes (isolated from 45% of patients), Streptococcus milleri group orga
nisms (27%), Haemophilus influenzae (11%), and viridans streptococci (
11%). Anaerobes were isolated from 82% of the samples and as a sole fi
nding from 15 abscesses. Fusobacterium necrophorum and Prevotella mela
ninogenica were both isolated from 38% of patients, Prevotella interme
dia from 32%, Peptostreptococcus micros from 27%, Fusobacterium nuclea
tum from 26%, and Actinomyces odontolyticus from 23%. The rate of prev
ious tonsillar/peritonsillar infections was lowest (25%) among patient
s infected with S. pyogenes and highest (52%) among those infected wit
h F. necrophorum (P < .01). Recurrences and/or related tonsillectomies
were more common among patients infected with F. necrophorum than amo
ng those infected with S. pyogenes (57% vs. 19%; P < .0001) or with S.
milleri group organisms (43% vs. 19%; P < .05). Beta-Lactamase was pr
oduced by only 38% of the 73 isolates of Prevotella species tested; ho
wever, 56% of the 36 patients studied harbored one or more such strain
s.